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Doublet stimulation increases Ca(2+) binding to troponin C to ensure rapid force development in skeletal muscle

Fast-twitch skeletal muscle fibers are often exposed to motor neuron double discharges (≥200 Hz), which markedly increase both the rate of contraction and the magnitude of the resulting force responses. However, the mechanism responsible for these effects is poorly understood, likely because of tech...

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Detalles Bibliográficos
Autores principales: Bakker, Anthony J., Cully, Tanya R., Wingate, Catherine D., Barclay, Christopher J., Launikonis, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339514/
https://www.ncbi.nlm.nih.gov/pubmed/28209802
http://dx.doi.org/10.1085/jgp.201611727