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Doublet stimulation increases Ca(2+) binding to troponin C to ensure rapid force development in skeletal muscle
Fast-twitch skeletal muscle fibers are often exposed to motor neuron double discharges (≥200 Hz), which markedly increase both the rate of contraction and the magnitude of the resulting force responses. However, the mechanism responsible for these effects is poorly understood, likely because of tech...
Autores principales: | Bakker, Anthony J., Cully, Tanya R., Wingate, Catherine D., Barclay, Christopher J., Launikonis, Bradley S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339514/ https://www.ncbi.nlm.nih.gov/pubmed/28209802 http://dx.doi.org/10.1085/jgp.201611727 |
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