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Metabonomics Research Progress on Liver Diseases
Metabolomics as the new omics technique develops after genomics, transcriptomics, and proteomics and has rapid development at present. Liver diseases are worldwide public health problems. In China, chronic hepatitis B and its secondary diseases are the common liver diseases. They can be diagnosed by...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339575/ https://www.ncbi.nlm.nih.gov/pubmed/28321390 http://dx.doi.org/10.1155/2017/8467192 |
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author | Yu, Mengqian Zhu, Ying Cong, Qingwei Wu, Chunyan |
author_facet | Yu, Mengqian Zhu, Ying Cong, Qingwei Wu, Chunyan |
author_sort | Yu, Mengqian |
collection | PubMed |
description | Metabolomics as the new omics technique develops after genomics, transcriptomics, and proteomics and has rapid development at present. Liver diseases are worldwide public health problems. In China, chronic hepatitis B and its secondary diseases are the common liver diseases. They can be diagnosed by the combination of history, virology, liver function, and medical imaging. However, some patients seldom have relevant physical examination, so the diagnosis may be delayed. Many other liver diseases, such as drug-induced liver injury (DILI), alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD), and autoimmune liver diseases, still do not have definite diagnostic markers; the diagnosis consists of history, medical imaging, and the relevant score. As a result, the clinical work becomes very complex. So it has broad prospects to explore the specific and sensitive biomarkers of liver diseases with metabolomics. In this paper, there are several summaries which are related to the current research progress and application of metabolomics on biomarkers of liver diseases. |
format | Online Article Text |
id | pubmed-5339575 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-53395752017-03-20 Metabonomics Research Progress on Liver Diseases Yu, Mengqian Zhu, Ying Cong, Qingwei Wu, Chunyan Can J Gastroenterol Hepatol Review Article Metabolomics as the new omics technique develops after genomics, transcriptomics, and proteomics and has rapid development at present. Liver diseases are worldwide public health problems. In China, chronic hepatitis B and its secondary diseases are the common liver diseases. They can be diagnosed by the combination of history, virology, liver function, and medical imaging. However, some patients seldom have relevant physical examination, so the diagnosis may be delayed. Many other liver diseases, such as drug-induced liver injury (DILI), alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD), and autoimmune liver diseases, still do not have definite diagnostic markers; the diagnosis consists of history, medical imaging, and the relevant score. As a result, the clinical work becomes very complex. So it has broad prospects to explore the specific and sensitive biomarkers of liver diseases with metabolomics. In this paper, there are several summaries which are related to the current research progress and application of metabolomics on biomarkers of liver diseases. Hindawi Publishing Corporation 2017 2017-02-21 /pmc/articles/PMC5339575/ /pubmed/28321390 http://dx.doi.org/10.1155/2017/8467192 Text en Copyright © 2017 Mengqian Yu et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Yu, Mengqian Zhu, Ying Cong, Qingwei Wu, Chunyan Metabonomics Research Progress on Liver Diseases |
title | Metabonomics Research Progress on Liver Diseases |
title_full | Metabonomics Research Progress on Liver Diseases |
title_fullStr | Metabonomics Research Progress on Liver Diseases |
title_full_unstemmed | Metabonomics Research Progress on Liver Diseases |
title_short | Metabonomics Research Progress on Liver Diseases |
title_sort | metabonomics research progress on liver diseases |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339575/ https://www.ncbi.nlm.nih.gov/pubmed/28321390 http://dx.doi.org/10.1155/2017/8467192 |
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