Monoclonal gammopathy of renal significance: Diagnostic workup

The clinical spectrum of diseases associated with monoclonal gammopathies is wide and they are most commonly the consequence of renal deposition of monoclonal immunoglobulin or its components. The differential diagnosis is difficult and renal biopsy is essential. To distinguish many of these patholo...

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Detalles Bibliográficos
Autores principales: Correia, Sofia O, Santos, Sofia, Malheiro, Jorge, Cabrita, António, Martins, La Salete, Santos, Josefina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339639/
https://www.ncbi.nlm.nih.gov/pubmed/28316940
http://dx.doi.org/10.5527/wjn.v6.i2.72
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author Correia, Sofia O
Santos, Sofia
Malheiro, Jorge
Cabrita, António
Martins, La Salete
Santos, Josefina
author_facet Correia, Sofia O
Santos, Sofia
Malheiro, Jorge
Cabrita, António
Martins, La Salete
Santos, Josefina
author_sort Correia, Sofia O
collection PubMed
description The clinical spectrum of diseases associated with monoclonal gammopathies is wide and they are most commonly the consequence of renal deposition of monoclonal immunoglobulin or its components. The differential diagnosis is difficult and renal biopsy is essential. To distinguish many of these pathologies is necessary to use techniques that are not always available, even in tertiary central hospitals. This review will discuss the clinical presentation, pathologic features, treatment, prognosis and common diagnostic difficulties of these entities.
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spelling pubmed-53396392017-03-17 Monoclonal gammopathy of renal significance: Diagnostic workup Correia, Sofia O Santos, Sofia Malheiro, Jorge Cabrita, António Martins, La Salete Santos, Josefina World J Nephrol Minireviews The clinical spectrum of diseases associated with monoclonal gammopathies is wide and they are most commonly the consequence of renal deposition of monoclonal immunoglobulin or its components. The differential diagnosis is difficult and renal biopsy is essential. To distinguish many of these pathologies is necessary to use techniques that are not always available, even in tertiary central hospitals. This review will discuss the clinical presentation, pathologic features, treatment, prognosis and common diagnostic difficulties of these entities. Baishideng Publishing Group Inc 2017-03-06 2017-03-06 /pmc/articles/PMC5339639/ /pubmed/28316940 http://dx.doi.org/10.5527/wjn.v6.i2.72 Text en ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Minireviews
Correia, Sofia O
Santos, Sofia
Malheiro, Jorge
Cabrita, António
Martins, La Salete
Santos, Josefina
Monoclonal gammopathy of renal significance: Diagnostic workup
title Monoclonal gammopathy of renal significance: Diagnostic workup
title_full Monoclonal gammopathy of renal significance: Diagnostic workup
title_fullStr Monoclonal gammopathy of renal significance: Diagnostic workup
title_full_unstemmed Monoclonal gammopathy of renal significance: Diagnostic workup
title_short Monoclonal gammopathy of renal significance: Diagnostic workup
title_sort monoclonal gammopathy of renal significance: diagnostic workup
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339639/
https://www.ncbi.nlm.nih.gov/pubmed/28316940
http://dx.doi.org/10.5527/wjn.v6.i2.72
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