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Using Data from Macaques To Predict Gamma Interferon Responses after Mycobacterium bovis BCG Vaccination in Humans: a Proof-of-Concept Study of Immunostimulation/Immunodynamic Modeling Methods
Macaques play a central role in the development of human tuberculosis (TB) vaccines. Immune and challenge responses differ across macaque and human subpopulations. We used novel immunostimulation/immunodynamic modeling methods in a proof-of-concept study to determine which macaque subpopulations bes...
Autores principales: | Rhodes, Sophie J., Sarfas, Charlotte, Knight, Gwenan M., White, Andrew, Pathan, Ansar A., McShane, Helen, Evans, Thomas G., Fletcher, Helen, Sharpe, Sally, White, Richard G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339646/ https://www.ncbi.nlm.nih.gov/pubmed/28077441 http://dx.doi.org/10.1128/CVI.00525-16 |
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