Gestational diabetes leads to down-regulation of CDK4-pRB-E2F1 pathway genes in pancreatic islets of rat offspring

OBJECTIVE(S): The link between a hyperglycemic intrauterine environment and the development of diabetes later in life has been observed in offspring exposed to gestational diabetes mellitus (GDM), but the underlying mechanisms for this phenomenon are still not clear. Reduced β-cells mass is a determ...

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Detalles Bibliográficos
Autores principales: Nazari, Zahra, Nabiuni, Mohammad, Saeidi, Mohsen, Golalipour, Mohammad Jafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339655/
https://www.ncbi.nlm.nih.gov/pubmed/28293391
http://dx.doi.org/10.22038/ijbms.2017.8240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339655/
https://www.ncbi.nlm.nih.gov/pubmed/28293391
http://dx.doi.org/10.22038/ijbms.2017.8240

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