ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans

Nonimmunological connective tissue phenotypes in humans are common among some congenital and acquired allergic diseases. Several of these congenital disorders have been associated with either increased TGF-β activity or impaired STAT3 activation, suggesting that these pathways might intersect and th...

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Detalles Bibliográficos
Autores principales: Lyons, J.J., Liu, Y., Ma, C.A., Yu, X., O’Connell, M.P., Lawrence, M.G., Zhang, Y., Karpe, K., Zhao, M., Siegel, A.M., Stone, K.D., Nelson, C., Jones, N., DiMaggio, T., Darnell, D.N., Mendoza-Caamal, E., Orozco, L., Hughes, J.D., McElwee, J., Hohman, R.J., Frischmeyer-Guerrerio, P.A., Rothenberg, M.E., Freeman, A.F., Holland, S.M., Milner, J.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339676/
https://www.ncbi.nlm.nih.gov/pubmed/28126831
http://dx.doi.org/10.1084/jem.20161435

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