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Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations

Activation of extrasynaptic N-methyl-d-aspartate (NMDA) receptors causes neurodegeneration and cell death. The disease mechanism involves a pathological triad consisting of mitochondrial dysfunction, loss of integrity of neuronal structures and connectivity, and disruption of excitation–transcriptio...

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Detalles Bibliográficos
Autor principal:	Bading, Hilmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339681/ https://www.ncbi.nlm.nih.gov/pubmed/28209726 http://dx.doi.org/10.1084/jem.20161673

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