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CCN1 promotes IL-1β production in keratinocytes by activating p38 MAPK signaling in psoriasis
CCN1, an extracellular protein also known as cysteine-rich protein 61 (Cyr61), is a novel pro-inflammatory factor involved in the pathogenesis of rheumatoid arthritis. As an inflammatory disease, psoriasis is characterized by keratinocyte activation-induced epidermal hyperplasia and cytokine-mediate...
Autores principales: | Sun, Yue, Zhang, Jie, Zhai, Tianhang, Li, Huidan, Li, Haichuan, Huo, Rongfen, Shen, Baihua, Wang, Beiqing, Chen, Xiangdong, Li, Ningli, Teng, Jialin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339692/ https://www.ncbi.nlm.nih.gov/pubmed/28266627 http://dx.doi.org/10.1038/srep43310 |
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