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Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE

Modelling Down syndrome (DS) in mouse has been crucial for the understanding of the disease and the evaluation of therapeutic targets. Nevertheless, the modelling so far has been limited to the mouse and, even in this model, generating duplication of genomic regions has been labour intensive and tim...

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Detalles Bibliográficos
Autores principales:	Birling, Marie-Christine, Schaeffer, Laurence, André, Philippe, Lindner, Loic, Maréchal, Damien, Ayadi, Abdel, Sorg, Tania, Pavlovic, Guillaume, Hérault, Yann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339700/ https://www.ncbi.nlm.nih.gov/pubmed/28266534 http://dx.doi.org/10.1038/srep43331

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