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Polymorphisms and Pharmacogenomics for the Clinical Efficacy of Methotrexate in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis

Methotrexate (MTX) is widely used and considered a first-line disease modifying anti-rheumatic drug (DMARD) for the treatment of rheumatoid arthritis (RA). Many of the relevant genes have been investigated to estimate the association between gene polymorphisms and MTX effectiveness in RA patients, a...

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Detalles Bibliográficos
Autores principales: Qiu, Qi, Huang, Jing, Shu, Xiaoming, Fan, Huizheng, Zhou, Youwen, Xiao, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339794/
https://www.ncbi.nlm.nih.gov/pubmed/28266606
http://dx.doi.org/10.1038/srep44015

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