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Interferon regulatory factor-1 activates autophagy to aggravate hepatic ischemia-reperfusion injury via the P38/P62 pathway in mice

Increasing evidence has linked autophagy to a detrimental role in hepatic ischemia- reperfusion (IR) injury (IRI). Here we focus on the role of interferon regulatory factor-1 (IRF-1) in regulating autophagy to aggravate hepatic IRI. We found that IRF-1 was up-regulated during hepatic IRI and was ass...

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Detalles Bibliográficos
Autores principales:	Yu, Yao, Li, Shipeng, Wang, Zhen, He, Jindan, Ding, Yijie, Zhang, Haiming, Yu, Wenli, Shi, Yiwei, Cui, Zilin, Wang, Ximo, Wang, Zhiliang, Sun, Liying, Zhang, Rongxin, Du, Hongyin, Zhu, Zhijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339805/ https://www.ncbi.nlm.nih.gov/pubmed/28266555 http://dx.doi.org/10.1038/srep43684

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