Human amniotic fluid contaminants alter thyroid hormone signalling and early brain development in Xenopus embryos

Thyroid hormones are essential for normal brain development in vertebrates. In humans, abnormal maternal thyroid hormone levels during early pregnancy are associated with decreased offspring IQ and modified brain structure. As numerous environmental chemicals disrupt thyroid hormone signalling, we q...

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Detalles Bibliográficos
Autores principales: Fini, Jean-Baptiste, Mughal, Bilal B., Le Mével, Sébastien, Leemans, Michelle, Lettmann, Mélodie, Spirhanzlova, Petra, Affaticati, Pierre, Jenett, Arnim, Demeneix, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339866/
https://www.ncbi.nlm.nih.gov/pubmed/28266608
http://dx.doi.org/10.1038/srep43786

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