Identifying ionic interactions within a membrane using BLaTM, a genetic tool to measure homo- and heterotypic transmembrane helix-helix interactions

The assembly of integral membrane protein complexes is frequently supported by transmembrane domain (TMD) interactions. Here, we present the BLaTM assay that measures homotypic as well as heterotypic TMD-TMD interactions in a bacterial membrane. The system is based on complementation of β-lactamase...

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Detalles Bibliográficos
Autores principales: Schanzenbach, Christoph, Schmidt, Fabian C., Breckner, Patrick, Teese, Mark G., Langosch, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339904/
https://www.ncbi.nlm.nih.gov/pubmed/28266525
http://dx.doi.org/10.1038/srep43476

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