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RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells

Myeloid-derived-suppressor cells (MDSCs) are key mediators of immune suppression in the ovarian tumor microenvironment. Modulation of MDSC function to relieve immunosuppression may enhance the immunologic clearance of tumors. The bis-benzylidine piperidone RA190 binds to the ubiquitin receptor RPN13...

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Detalles Bibliográficos
Autores principales:	Soong, Ruey-Shyang, Anchoori, Ravi K., Yang, Benjamin, Yang, Andrew, Tseng, Ssu-Hsueh, He, Liangmei, Tsai, Ya-Chea, Roden, Richard B.S., Hung, Chien-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340091/ https://www.ncbi.nlm.nih.gov/pubmed/27655678 http://dx.doi.org/10.18632/oncotarget.12095

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