DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells

Wnt signaling plays an important role in breast carcinogenesis. DAPPER2 (DACT2) functions as an inhibitor of canonical Wnt signaling and plays distinct roles in different cell contexts, with its role in breast tumorigenesis unclear. We investigated DACT2 expression in breast cancer cell lines and pr...

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Detalles Bibliográficos
Autores principales: Xiang, Tingxiu, Fan, Yichao, Li, Chunhong, Li, Lili, Ying, Ying, Mu, Junhao, Peng, Weiyan, Feng, Yixiao, Oberst, Michael, Kelly, Kathleen, Ren, Guosheng, Tao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340116/
https://www.ncbi.nlm.nih.gov/pubmed/27708215
http://dx.doi.org/10.18632/oncotarget.12341

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