Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration

RNA editing in mammals is a form of post-transcriptional modification in which adenosine is converted to inosine by the adenosine deaminases acting on RNA (ADAR) family of enzymes. Based on evidence of altered ADAR expression in epithelial ovarian cancers (EOC), we hypothesized that single nucleotid...

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Autores principales: Permuth, Jennifer B., Reid, Brett, Earp, Madalene, Chen, Y. Ann, Monteiro, Alvaro N.A., Chen, Zhihua, Group, AOCS Study, Chenevix-Trench, Georgia, Fasching, Peter A., Beckmann, Matthias W., Lambrechts, Diether, Vanderstichele, Adriaan, Niewenhuyse, Els Van, Vergote, Ignace, Rossing, Mary Anne, Doherty, Jennifer Anne, Chang-Claude, Jenny, Moysich, Kirsten, Odunsi, Kunle, Goodman, Marc T., Shvetsov, Yurii B., Wilkens, Lynne R., Thompson, Pamela J., Dörk, Thilo, Bogdanova, Natalia, Butzow, Ralf, Nevanlinna, Heli, Pelttari, Liisa, Leminen, Arto, Modugno, Francesmary, Edwards, Robert P., Ness, Roberta B., Kelley, Joseph, Heitz, Florian, Karlan, Beth, Lester, Jenny, Kjaer, Susanne K., Jensen, Allan, Giles, Graham, Hildebrandt, Michelle, Liang, Dong, Lu, Karen H., Wu, Xifeng, Levine, Douglas A., Bisogna, Maria, Berchuck, Andrew, Cramer, Daniel W., Terry, Kathryn L., Tworoger, Shelley S., Poole, Elizabeth M., Bandera, Elisa V., Fridley, Brooke, Cunningham, Julie, Winham, Stacey J., Olson, Sara H., Orlow, Irene, Bjorge, Line, Kiemeney, Lambertus A., Massuger, Leon, Pejovic, Tanja, Moffitt, Melissa, Le, Nhu, Cook, Linda S., Brooks-Wilson, Angela, Kelemen, Linda E., Gronwald, Jacek, Lubinski, Jan, Wentzensen, Nicolas, Brinton, Louise A., Lissowska, Jolanta, Yang, Hanna, Hogdall, Estrid, Hogdall, Claus, Lundvall, Lene, Pharoah, Paul D.P., Song, Honglin, Campbell, Ian, Eccles, Diana, McNeish, Iain, Whittemore, Alice, McGuire, Valerie, Sieh, Weiva, Rothstein, Joseph, Phelan, Catherine M., Risch, Harvey, Narod, Steven, McLaughlin, John, Anton-Culver, Hoda, Ziogas, Argyrios, Menon, Usha, Gayther, Simon, Ramus, Susan J., Gentry-Maharaj, Aleksandra, Pearce, Celeste Leigh, Wu, Anna H., Kupryjanczyk, Jolanta, Dansonka-Mieszkowska, Agnieszka, Schildkraut, Joellen M., Cheng, Jin Q., Goode, Ellen L., Sellers, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340123/
https://www.ncbi.nlm.nih.gov/pubmed/27911851
http://dx.doi.org/10.18632/oncotarget.10546

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