Cargando…

Serum APE1 as a predictive marker for platinum-based chemotherapy of non-small cell lung cancer patients

PURPOSE: To define the role of the DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in predicting the prognosis and chemotherapeutic response of non-small cell lung cancer patients receiving platinum-containing chemotherapy. RESULTS: Our investigations found that serum APE1 level was s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shiheng, He, Le, Dai, Nan, Guan, Wei, Shan, Jinlu, Yang, Xueqin, Zhong, Zhaoyang, Qing, Yi, Jin, Feng, Chen, Chuan, Yang, Yuxin, Wang, Hongyi, Baugh, Laura, Tell, Gianluca, Wilson, David M., Li, Mengxia, Wang, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340230/ https://www.ncbi.nlm.nih.gov/pubmed/27813497 http://dx.doi.org/10.18632/oncotarget.13030

Ejemplares similares

The regulatory role of APE1 in epithelial‐to‐mesenchymal transition and in determining EGFR‐TKI responsiveness in non‐small‐cell lung cancer
por: Yang, Xiao, et al.
Publicado: (2018)

APE1 deficiency promotes cellular senescence and premature aging features
por: Li, Mengxia, et al.
Publicado: (2018)

Distinct APE1 Activities Affect the Regulation of VEGF Transcription Under Hypoxic Conditions
por: Li, Mengxia, et al.
Publicado: (2019)

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
por: Antoniali, Giulia, et al.
Publicado: (2017)

Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming growth factor β-dependent manner in human osteosarcoma
por: Jiang, Xuan, et al.
Publicado: (2015)

APE1 may influence CD4+ naïve T cells on recurrence free survival in early stage NSCLC
por: Li, Yanping, et al.
Publicado: (2021)

Polymorphisms of BCL2 and BAX Genes Associate with Outcomes in Advanced Non-small cell lung cancer Patients treated with platinum-based Chemotherapy
por: Peng, Yu, et al.
Publicado: (2015)

miR-513a-5p regulates radiosensitivity of osteosarcoma by targeting human apurinic/apyrimidinic endonuclease
por: Dai, Nan, et al.
Publicado: (2016)

MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression
por: Liang, Wei, et al.
Publicado: (2019)

APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC
por: Malfatti, Matilde Clarissa, et al.
Publicado: (2019)

Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer
por: Ren, Tao, et al.
Publicado: (2015)

Mitochondrial translocation of APE1 relies on the MIA pathway
por: Barchiesi, Arianna, et al.
Publicado: (2015)

Apurinic/apyrimidinic endonuclease 1 induced upregulation of fibroblast growth factor 2 and its receptor 3 induces angiogenesis in human osteosarcoma cells
por: Ren, Tao, et al.
Publicado: (2014)

Lost expression of ADAMTS5 protein associates with progression and poor prognosis of hepatocellular carcinoma
por: Li, Chongyi, et al.
Publicado: (2015)

APE1 controls DICER1 expression in NSCLC through miR-33a and miR-130b
por: Antoniali, Giulia, et al.
Publicado: (2022)

Revisiting Two Decades of Research Focused on Targeting APE1 for Cancer Therapy: The Pros and Cons
por: Malfatti, Matilde Clarissa, et al.
Publicado: (2023)

Silencing of APE1 Enhances Sensitivity of Human Hepatocellular Carcinoma Cells to Radiotherapy In Vitro and in a Xenograft Model
por: Cun, Yanping, et al.
Publicado: (2013)

Architecture of The Human Ape1 Interactome Defines Novel Cancers Signatures
por: Ayyildiz, Dilara, et al.
Publicado: (2020)

APE1 polymorphic variants cause persistent genomic stress and affect cancer cell proliferation
por: Lirussi, Lisa, et al.
Publicado: (2016)

HLA-DQB1 expression on tumor cells is a novel favorable prognostic factor for relapse in early-stage lung adenocarcinoma
por: Zhang, Liang, et al.
Publicado: (2019)

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function
por: Vascotto, Carlo, et al.
Publicado: (2011)

Functional Assessment of Population and Tumor-Associated APE1 Protein Variants
por: Illuzzi, Jennifer L., et al.
Publicado: (2013)

A randomized, double-blind, placebo-controlled study of B-cell lymphoma 2 homology 3 mimetic gossypol combined with docetaxel and cisplatin for advanced non-small cell lung cancer with high expression of apurinic/apyrimidinic endonuclease 1
por: Wang, Yuxiao, et al.
Publicado: (2020)

Transcatheter rectal arterial chemoembolization with oxaliplatin plus S-1 concurrent chemoradiotherapy can improve the pathological remission rate in locally advanced rectal cancer: a comparative study
por: Yang, Bo, et al.
Publicado: (2020)

From APE to APE-100: present and future of the APE project
por: Bacilieri, P, et al.
Publicado: (1988)

Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma
por: Pascut, Devis, et al.
Publicado: (2019)

Cleavage of the APE1 N-Terminal Domain in Acute Myeloid Leukemia Cells Is Associated with Proteasomal Activity
por: Lirussi, Lisa, et al.
Publicado: (2020)

Apes
por: Lowenstine, Linda J., et al.
Publicado: (2018)

Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2
por: Malfatti, Matilde Clarissa, et al.
Publicado: (2017)

Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
por: Pines, Alex, et al.
Publicado: (2005)

Nimotuzumab plus platinum-based chemotherapy versus platinum-based chemotherapy alone in patients with recurrent or metastatic nasopharyngeal carcinoma
por: Zhu, Yunshu, et al.
Publicado: (2020)

Man-Apes or Ape-Men? The Story of Discoveries in Africa
por: Gardner, William U.
Publicado: (1967)

Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis
por: Di Maso, Vittorio, et al.
Publicado: (2015)

APE1 stimulates EGFR-TKI resistance by activating Akt signaling through a redox-dependent mechanism in lung adenocarcinoma
por: Lu, Guo-Shou, et al.
Publicado: (2018)

Identification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor
por: Qian, Chengyuan, et al.
Publicado: (2014)

Mitochondrial APE1 promotes cisplatin resistance by downregulating ROS in osteosarcoma
por: Liu, Yufeng, et al.
Publicado: (2020)

The mentality of apes
por: Köhler, Wolfgang, 1887-1967
Publicado: (1959)

The naked ape
por: Morris, Desmond
Publicado: (1967)

Men and apes
por: Morris, Ramona
Publicado: (1966)

The apes of God /
por: Lewis, Wyndham, 1882-1957

Cannot write session to /tmp/vufind_sessions/sess_e8p44p2te7nppm5qupv55qecd3