Cargando…

Alternative therapies for metastatic breast cancer: multimodal approach targeting tumor cell heterogeneity

One of the primary challenges in developing effective therapies for malignant tumors is the specific targeting of a heterogeneous cancer cell population within the tumor. The cancerous tumor is made up of a variety of distinct cells with specialized receptors and proteins that could potentially be v...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sambi, Manpreet, Haq, Sabah, Samuel, Vanessa, Qorri, Bessi, Haxho, Fiona, Hill, Kelli, Harless, William, Szewczuk, Myron R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340247/ https://www.ncbi.nlm.nih.gov/pubmed/28280388 http://dx.doi.org/10.2147/BCTT.S130838

Ejemplares similares

A Triple Combination of Metformin, Acetylsalicylic Acid, and Oseltamivir Phosphate Impacts Tumour Spheroid Viability and Upends Chemoresistance in Triple-Negative Breast Cancer
por: Sambi, Manpreet, et al.
Publicado: (2020)

Novel Molecular Mechanism of Aspirin and Celecoxib Targeting Mammalian Neuraminidase-1 Impedes Epidermal Growth Factor Receptor Signaling Axis and Induces Apoptosis in Pancreatic Cancer Cells
por: Qorri, Bessi, et al.
Publicado: (2020)

Next Generation of Cancer Drug Repurposing: Therapeutic Combination of Aspirin and Oseltamivir Phosphate Potentiates Gemcitabine to Disable Key Survival Pathways Critical for Pancreatic Cancer Progression
por: Qorri, Bessi, et al.
Publicado: (2022)

Repositioning of Old Drugs for Novel Cancer Therapies: Continuous Therapeutic Perfusion of Aspirin and Oseltamivir Phosphate with Gemcitabine Treatment Disables Tumor Progression, Chemoresistance, and Metastases
por: Qorri, Bessi, et al.
Publicado: (2022)

Novel Therapeutic Target Critical for SARS-CoV-2 Infectivity and Induction of the Cytokine Release Syndrome
por: Harless, William W., et al.
Publicado: (2023)

Current Challenges in Cancer Immunotherapy: Multimodal Approaches to Improve Efficacy and Patient Response Rates
por: Sambi, Manpreet, et al.
Publicado: (2019)

Therapeutic potential of medicinal marijuana: an educational primer for health care professionals
por: Mouhamed, Yara, et al.
Publicado: (2018)

3D Multicellular Stem-Like Human Breast Tumor Spheroids Enhance Tumorigenicity of Orthotopic Xenografts in Athymic Nude Rat Model
por: Mokhtari, Reza Bayat, et al.
Publicado: (2021)

The Biased G-Protein-Coupled Receptor Agonism Bridges the Gap between the Insulin Receptor and the Metabolic Syndrome
por: Liauchonak, Iryna, et al.
Publicado: (2018)

Sialylation transmogrifies human breast and pancreatic cancer cells into 3D multicellular tumor spheroids using cyclic RGD-peptide induced self-assembly
por: Akasov, Roman, et al.
Publicado: (2016)

Sialylation facilitates self-assembly of 3D multicellular prostaspheres by using cyclo-RGDfK(TPP) peptide
por: Haq, Sabah, et al.
Publicado: (2017)

The crucial role of primary care providers in the long-term follow-up of adult survivors of childhood cancer
por: Jain, Justin, et al.
Publicado: (2019)

The Next-Generation of Combination Cancer Immunotherapy: Epigenetic Immunomodulators Transmogrify Immune Training to Enhance Immunotherapy
por: Mokhtari, Reza Bayat, et al.
Publicado: (2021)

Next-Generation Multimodality of Nanomedicine Therapy: Size and Structure Dependence of Folic Acid Conjugated Copolymers Actively Target Cancer Cells in Disabling Cell Division and Inducing Apoptosis
por: Sambi, Manpreet, et al.
Publicado: (2019)

Non-Nutritive Sweeteners and Their Implications on the Development of Metabolic Syndrome
por: Liauchonak, Iryna, et al.
Publicado: (2019)

Neuraminidase-1: A novel therapeutic target in multistage tumorigenesis
por: Haxho, Fiona, et al.
Publicado: (2016)

Recent advances in “smart” delivery systems for extended drug release in cancer therapy
por: Kalaydina, Regina-Veronicka, et al.
Publicado: (2018)

Agonist-Biased Signaling via Matrix Metalloproteinase-9 Promotes Extracellular Matrix Remodeling
por: Qorri, Bessi, et al.
Publicado: (2018)

Functionalized Folic Acid-Conjugated Amphiphilic Alternating Copolymer Actively Targets 3D Multicellular Tumour Spheroids and Delivers the Hydrophobic Drug to the Inner Core
por: Li, Xia, et al.
Publicado: (2018)

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis
por: Mokhtari, Reza Bayat, et al.
Publicado: (2021)

Correction: Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis
por: Mokhtari, Reza Bayat, et al.
Publicado: (2022)

Oseltamivir phosphate monotherapy ablates tumor neovascularization, growth, and metastasis in mouse model of human triple-negative breast adenocarcinoma
por: Haxho, Fiona, et al.
Publicado: (2014)

The Hippo Pathway Effectors YAP/TAZ-TEAD Oncoproteins as Emerging Therapeutic Targets in the Tumor Microenvironment
por: Mokhtari, Reza Bayat, et al.
Publicado: (2023)

Therapeutic designed poly (lactic-co-glycolic acid) cylindrical oseltamivir phosphate-loaded implants impede tumor neovascularization, growth and metastasis in mouse model of human pancreatic carcinoma
por: Hrynyk, Michael, et al.
Publicado: (2015)

Transcriptional factor snail controls tumor neovascularization, growth and metastasis in mouse model of human ovarian carcinoma
por: Abdulkhalek, Samar, et al.
Publicado: (2014)

Folic acid-conjugated amphiphilic alternating copolymer as a new active tumor targeting drug delivery platform
por: Li, Xia, et al.
Publicado: (2016)

Metamorphic Effect of Angiogenic Switch in Tumor Development: Conundrum of Tumor Angiogenesis Toward Progression and Metastatic Potential
por: Moshe, Daniel Leon, et al.
Publicado: (2023)

Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors
por: Sambi, Manpreet, et al.
Publicado: (2017)

Neu1 sialidase and matrix metalloproteinase-9 cross-talk in alliance with insulin receptors is an essential molecular signaling platform for insulin-induced receptor activation
por: Alghamdi, Farah G, et al.
Publicado: (2014)

Editorial: Recent advancements in neoadjuvant chemotherapy for specific breast cancer subtypes
por: Adham, Sirin A., et al.
Publicado: (2022)

Cancer treatments transform residual cancer cell phenotype
por: Harless, William W
Publicado: (2011)

Revisiting perioperative chemotherapy: the critical importance of targeting residual cancer prior to wound healing
por: Harless, William W
Publicado: (2009)

Cannabinoids Transmogrify Cancer Metabolic Phenotype via Epigenetic Reprogramming and a Novel CBD Biased G Protein-Coupled Receptor Signaling Platform
por: Bunsick, David A., et al.
Publicado: (2023)

Insulin Receptor Signaling in Health and Disease
por: Baghaie, Leili, et al.
Publicado: (2023)

Understanding heterogeneous tumor microenvironment in metastatic melanoma
por: Yan, Yiyi, et al.
Publicado: (2019)

Multimodal Imaging and Management of a Metastatic Cardiac Intimal Sarcoma
por: Ballout, Jad A., et al.
Publicado: (2023)

Integrating multimodal data through interpretable heterogeneous ensembles
por: Li, Yan Chak, et al.
Publicado: (2022)

Integrating multimodal data through interpretable heterogeneous ensembles
por: Li, Yan Chak, et al.
Publicado: (2022)

Multimodal therapy in the treatment of metastatic prostate cancer: A case report
por: Omidele, Olamide O., et al.
Publicado: (2018)

Heterogeneous response to target therapy in metastatic papillary renal cell carcinoma evaluated by morphologic and metabolic multimodality imaging: A case report
por: Naglieri, Emanuele, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9g5acv114g61d0dl7dctflpgu1