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ERBB2 mutation is associated with a worse prognosis in patients with CDH1 altered invasive lobular cancer of the breast
E-cadherin (CDH1) is a glycoprotein that mediates adhesion between epithelial cells and also suppresses cancer invasion. Mutation or deletion of the CDH1 gene has been reported in 30–60% cases of invasive lobular carcinoma (ILC). However, little is known about genomic differences between ILC with an...
Autores principales: | Ping, Zheng, Siegal, Gene P., Harada, Shuko, Eltoum, Isam-Eldin, Youssef, Mariam, Shen, Tiansheng, He, Jianbo, Huang, Yingjie, Chen, Dongquan, Li, Yiping, Bland, Kirby I, Chang, Helena R, Shen, Dejun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340256/ https://www.ncbi.nlm.nih.gov/pubmed/27811364 http://dx.doi.org/10.18632/oncotarget.13019 |
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