Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells

Peripheral regulatory CD4(+) T cells (Treg cells) prevent maladaptive inflammatory responses to innocuous foreign antigens. Treg cell dysfunction has been linked to many inflammatory diseases, including allergic airway inflammation. Glucocorticoids that are used to treat allergic airway inflammation...

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Detalles Bibliográficos
Autores principales: Penberthy, Kristen Kelley, Buckley, Monica Weaver, Arandjelovic, Sanja, Ravichandran, Kodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340387/
https://www.ncbi.nlm.nih.gov/pubmed/28267764
http://dx.doi.org/10.1371/journal.pone.0173386

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