A genome wide association study identifies a lncRna as risk factor for pathological inflammatory responses in leprosy

Leprosy Type-1 Reactions (T1Rs) are pathological inflammatory responses that afflict a sub-group of leprosy patients and result in peripheral nerve damage. Here, we employed a family-based GWAS in 221 families with 229 T1R-affect offspring with stepwise replication to identify risk factors for T1R....

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Detalles Bibliográficos
Autores principales: Fava, Vinicius M., Manry, Jeremy, Cobat, Aurélie, Orlova, Marianna, Van Thuc, Nguyen, Moraes, Milton O., Sales-Marques, Carolinne, Stefani, Mariane M. A., Latini, Ana Carla P., Belone, Andrea F., Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340414/
https://www.ncbi.nlm.nih.gov/pubmed/28222097
http://dx.doi.org/10.1371/journal.pgen.1006637

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