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Expression Levels of GABA-A Receptor Subunit Alpha 3, Gabra3 and Lipoprotein Lipase, Lpl Are Associated with the Susceptibility to Acetaminophen-Induced Hepatotoxicity

Drug-induced liver injury (DILI) is the serious and fatal drug-associated adverse effect, but its incidence is very low and individual variation in severity is substantial. Acetaminophen (APAP)-induced liver injury accounts for >50% of reported DILI cases but little is known for the cause of indi...

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Detalles Bibliográficos
Autores principales: Kim, Minjeong, Yun, Jun-Won, Shin, Kyeho, Cho, Yejin, Yang, Mijeong, Nam, Ki Taek, Lim, Kyung-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340535/
https://www.ncbi.nlm.nih.gov/pubmed/27530116
http://dx.doi.org/10.4062/biomolther.2016.076