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Intranasal Administration of Interleukin-1 Receptor Antagonist in a Transient Focal Cerebral Ischemia Rat Model

The interleukin-1 receptor antagonist (IL-1RA) is a potential stroke treatment candidate. Intranasal delivery is a novel method thereby a therapeutic protein can be penetrated into the brain parenchyma by bypassing the blood-brain barrier. Thus, this study tested whether intranasal IL-1RA can provid...

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Detalles Bibliográficos
Autores principales:	Lee, Jae Hoon, Kam, Eun Hee, Kim, Jeong Min, Kim, So Yeon, Kim, Eun Jeong, Cheon, So Yeong, Koo, Bon-Nyeo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340539/ https://www.ncbi.nlm.nih.gov/pubmed/27530114 http://dx.doi.org/10.4062/biomolther.2016.050

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