Cargando…

Auranofin Suppresses Plasminogen Activator Inhibitor-2 Expression through Annexin A5 Induction in Human Prostate Cancer Cells

Auranofin has been developed as antirheumatic drugs, which is currently under clinical development for the treatment of chronic lymphocytic leukemia. Previous report showed that auranofin induced apoptosis by enhancement of annexin A5 expression in PC-3 cells. To understand the role of annexin A5 in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Dong-Won, Kwon, Yeo-Jung, Ye, Dong-Jin, Baek, Hyoung-Seok, Lee, Joo-Eun, Chun, Young-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340543/ https://www.ncbi.nlm.nih.gov/pubmed/27956714 http://dx.doi.org/10.4062/biomolther.2016.223

Ejemplares similares

Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells
por: Ryu, Yeon-Sang, et al.
Publicado: (2020)

Annexin A5 suppresses cyclooxygenase-2 expression by downregulating the protein kinase C-ζ–nuclear factor-κB signaling pathway in prostate cancer cells
por: Baek, Hyoung-Seok, et al.
Publicado: (2017)

Induction of Integrin Signaling by Steroid Sulfatase in Human Cervical Cancer Cells
por: Ye, Dong-Jin, et al.
Publicado: (2017)

Efficacy of auranofin as an inhibitor of desmoid progression
por: Ito, Kan, et al.
Publicado: (2022)

CYP1B1 Enhances Cell Proliferation and Metastasis through Induction of EMT and Activation of Wnt/β-Catenin Signaling via Sp1 Upregulation
por: Kwon, Yeo-Jung, et al.
Publicado: (2016)

Cyclic Voltammetry of Auranofin
por: Mohamed, Ahmed A., et al.
Publicado: (1999)

Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 Levels in Patients with Acute Paraquat Intoxication
por: Seok, Su-Jin, et al.
Publicado: (2011)

Annexin A5 as a New Potential Biomarker for Cisplatin-Induced Toxicity in Human Kidney Epithelial Cells
por: Kwon, Yeo-Jung, et al.
Publicado: (2013)

Association of pro-fibrinolytic receptor AnnexinA2 with tissue plasminogen activator/Inhibitor-1 in pre-eclampsia
por: Ruikar, Komal, et al.
Publicado: (2023)

Auranofin Inhibits RANKL-Induced Osteoclastogenesis by Suppressing Inhibitors of κB Kinase and Inflammasome-Mediated Interleukin-1β Secretion
por: Kim, Hyun Young, et al.
Publicado: (2019)

Combination of Auranofin and ICG-001 Suppress the Proliferation and Metastasis of Colon Cancer
por: Lin, Zhaoyan, et al.
Publicado: (2021)

Zinc-Triggered Induction of Tissue Plasminogen Activator and Plasminogen in Endothelial Cells and Pericytes
por: Cho, Mun-Kyung, et al.
Publicado: (2013)

Human steroid sulfatase induces Wnt/β-catenin signaling and epithelial-mesenchymal transition by upregulating Twist1 and HIF-1α in human prostate and cervical cancer cells
por: Shin, Sangyun, et al.
Publicado: (2017)

Seahorse-derived peptide suppresses invasive migration of HT1080 fibrosarcoma cells by competing with intracellular α-enolase for plasminogen binding and inhibiting uPA-mediated activation of plasminogen
por: Kim, Yong-Tae, et al.
Publicado: (2014)

Auranofin-Mediated NRF2 Induction Attenuates Interleukin 1 Beta Expression in Alveolar Macrophages
por: Wall, Stephanie B., et al.
Publicado: (2021)

Anti-fibrotic effect of aurocyanide, the active metabolite of auranofin
por: Kim, Hyun Young, et al.
Publicado: (2023)

Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer
por: Oh, Byung Moo, et al.
Publicado: (2017)

Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer
por: Oh, Byung Moo, et al.
Publicado: (2017)

Interplay of membrane crosslinking and curvature induction by annexins
por: Mularski, Anna, et al.
Publicado: (2022)

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth
por: Liu, Ningning, et al.
Publicado: (2014)

Prognostic significance of annexin A2 and annexin A4 expression in patients with cervical cancer
por: Choi, Chel Hun, et al.
Publicado: (2016)

Effects of Korean Red Ginseng extract on tissue plasminogen activator and plasminogen activator inhibitor-1 expression in cultured rat primary astrocytes
por: Ko, Hyun Myung, et al.
Publicado: (2013)

Induction of plasminogen activator synthesis by antibodies
Publicado: (1981)

Auranofin, a thioredoxin reductase inhibitor, causes platelet death through calcium overload
por: Harper, Matthew T.
Publicado: (2017)

Auranofin is a potent suppressor of osteosarcoma metastasis
por: Topkas, Eleni, et al.
Publicado: (2015)

Evaluation of Auranofin Loading within Ferritin Nanocages
por: Lucignano, Rosanna, et al.
Publicado: (2022)

Dual inhibition of thioredoxin reductase and proteasome is required for auranofin-induced paraptosis in breast cancer cells
por: Seo, Min Ji, et al.
Publicado: (2023)

Association between Plasma Levels of Plasminogen Activator Inhibitor-1 and Colorectal Neoplasms
por: Kim, Eun Ran, et al.
Publicado: (2013)

Tissue plasminogen activator and plasminogen activator inhibitor type 1 gene polymorphism in patients with gastric ulcer complicated with bleeding.
por: Kim, Hong-Soo, et al.
Publicado: (2003)

Transcriptional Upregulation of Plasminogen Activator Inhibitor-1 in Rat Primary Astrocytes by a Proteasomal Inhibitor MG132
por: Cho, Kyu Suk, et al.
Publicado: (2013)

Steroid sulfatase deficiency causes cellular senescence and abnormal differentiation by inducing Yippee-like 3 expression in human keratinocytes
por: Baek, Hyoung-Seok, et al.
Publicado: (2021)

LppA is a novel plasminogen receptor of Mycoplasma bovis that contributes to adhesion by binding the host extracellular matrix and Annexin A2
por: Liu, Shuang, et al.
Publicado: (2023)

In vitro antineoplastic effects of auranofin in canine lymphoma cells
por: Zhang, Hong, et al.
Publicado: (2018)

Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish
por: Leask, Megan, et al.
Publicado: (2021)

The gold complex auranofin: new perspectives for cancer therapy
por: Abdalbari, Farah H., et al.
Publicado: (2021)

Auranofin and Pharmacologic Ascorbate as Radiomodulators in the Treatment of Pancreatic Cancer
por: Steers, Garett J., et al.
Publicado: (2022)

Menadione Potentiates Auranofin-Induced Glioblastoma Cell Death
por: Szeliga, Monika, et al.
Publicado: (2022)

Auranofin attenuates hepatic steatosis and fibrosis in nonalcoholic fatty liver disease via NRF2 and NF-κB signaling pathways
por: Lee, Seung Min, et al.
Publicado: (2022)

Heparin‐binding Epidermal Growth Factor‐like Growth Factor: p91 Activation, Induction of Plasminogen Activator/Plasminogen Activator Inhibitor, and Tubular Morphogenesis in Human Microvascular Endothelial Cells
por: Ushiro, Shin, et al.
Publicado: (1996)

Combination Low-Dose Tissue-Type Plasminogen Activator Plus Annexin A2 for Improving Thrombolytic Stroke Therapy
por: Jiang, Yinghua, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_usoakbvcbguq0fffed8710289b