Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure

Systemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase...

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Detalles Bibliográficos
Autores principales: Premkumar, Madhumita, Rangegowda, Devaraja, Vyas, Tanmay, Kulkarni, Anand, Grover, Shrruti, Mahiwall, Rakhi, Sarin, Shiv Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340654/
https://www.ncbi.nlm.nih.gov/pubmed/28286788
http://dx.doi.org/10.14309/crj.2017.22
Descripción
Sumario:Systemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase are the most common clinical and biochemical findings, respectively. We report a case of systemic amyloidosis of AL that clinically presented as acute-on-chronic liver failure and resulted in a fatal clinical course in a 56-year-old man.

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