Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure
Systemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American College of Gastroenterology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340654/ https://www.ncbi.nlm.nih.gov/pubmed/28286788 http://dx.doi.org/10.14309/crj.2017.22 |
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author | Premkumar, Madhumita Rangegowda, Devaraja Vyas, Tanmay Kulkarni, Anand Grover, Shrruti Mahiwall, Rakhi Sarin, Shiv Kumar |
author_facet | Premkumar, Madhumita Rangegowda, Devaraja Vyas, Tanmay Kulkarni, Anand Grover, Shrruti Mahiwall, Rakhi Sarin, Shiv Kumar |
author_sort | Premkumar, Madhumita |
collection | PubMed |
description | Systemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase are the most common clinical and biochemical findings, respectively. We report a case of systemic amyloidosis of AL that clinically presented as acute-on-chronic liver failure and resulted in a fatal clinical course in a 56-year-old man. |
format | Online Article Text |
id | pubmed-5340654 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | American College of Gastroenterology |
record_format | MEDLINE/PubMed |
spelling | pubmed-53406542017-03-10 Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure Premkumar, Madhumita Rangegowda, Devaraja Vyas, Tanmay Kulkarni, Anand Grover, Shrruti Mahiwall, Rakhi Sarin, Shiv Kumar ACG Case Rep J Case Report Systemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase are the most common clinical and biochemical findings, respectively. We report a case of systemic amyloidosis of AL that clinically presented as acute-on-chronic liver failure and resulted in a fatal clinical course in a 56-year-old man. American College of Gastroenterology 2017-02-15 /pmc/articles/PMC5340654/ /pubmed/28286788 http://dx.doi.org/10.14309/crj.2017.22 Text en Copyright © Premkumar et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Case Report Premkumar, Madhumita Rangegowda, Devaraja Vyas, Tanmay Kulkarni, Anand Grover, Shrruti Mahiwall, Rakhi Sarin, Shiv Kumar Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure |
title | Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure |
title_full | Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure |
title_fullStr | Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure |
title_full_unstemmed | Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure |
title_short | Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure |
title_sort | primary hepatic amyloidosis presenting as acute-on-chronic liver failure |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340654/ https://www.ncbi.nlm.nih.gov/pubmed/28286788 http://dx.doi.org/10.14309/crj.2017.22 |
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