Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure

Systemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase...

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Autores principales: Premkumar, Madhumita, Rangegowda, Devaraja, Vyas, Tanmay, Kulkarni, Anand, Grover, Shrruti, Mahiwall, Rakhi, Sarin, Shiv Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340654/
https://www.ncbi.nlm.nih.gov/pubmed/28286788
http://dx.doi.org/10.14309/crj.2017.22
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author Premkumar, Madhumita
Rangegowda, Devaraja
Vyas, Tanmay
Kulkarni, Anand
Grover, Shrruti
Mahiwall, Rakhi
Sarin, Shiv Kumar
author_facet Premkumar, Madhumita
Rangegowda, Devaraja
Vyas, Tanmay
Kulkarni, Anand
Grover, Shrruti
Mahiwall, Rakhi
Sarin, Shiv Kumar
author_sort Premkumar, Madhumita
collection PubMed
description Systemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase are the most common clinical and biochemical findings, respectively. We report a case of systemic amyloidosis of AL that clinically presented as acute-on-chronic liver failure and resulted in a fatal clinical course in a 56-year-old man.
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spelling pubmed-53406542017-03-10 Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure Premkumar, Madhumita Rangegowda, Devaraja Vyas, Tanmay Kulkarni, Anand Grover, Shrruti Mahiwall, Rakhi Sarin, Shiv Kumar ACG Case Rep J Case Report Systemic amyloidosis of amyloid light chain associated protein (AL), also called primary amyloidosis, frequently involves the liver, but rarely causes clinically apparent liver disease. The more common presentation is with acute renal failure. Hepatomegaly and mild elevation of alkaline phosphatase are the most common clinical and biochemical findings, respectively. We report a case of systemic amyloidosis of AL that clinically presented as acute-on-chronic liver failure and resulted in a fatal clinical course in a 56-year-old man. American College of Gastroenterology 2017-02-15 /pmc/articles/PMC5340654/ /pubmed/28286788 http://dx.doi.org/10.14309/crj.2017.22 Text en Copyright © Premkumar et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Premkumar, Madhumita
Rangegowda, Devaraja
Vyas, Tanmay
Kulkarni, Anand
Grover, Shrruti
Mahiwall, Rakhi
Sarin, Shiv Kumar
Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure
title Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure
title_full Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure
title_fullStr Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure
title_full_unstemmed Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure
title_short Primary Hepatic Amyloidosis Presenting as Acute-on-Chronic Liver Failure
title_sort primary hepatic amyloidosis presenting as acute-on-chronic liver failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340654/
https://www.ncbi.nlm.nih.gov/pubmed/28286788
http://dx.doi.org/10.14309/crj.2017.22
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