Tubulointerstitial Nephritis as the Initial Presentation of Crohn’s Disease and Successful Treatment with Infliximab

Tubulointerstitial nephritis (TIN) is not commonly associated in aminosalicylate-naïve patients with Crohn’s disease (CD). Our case describes the initial presentation, diagnosis, and management of an adolescent presenting with TIN and underlying CD. Our case emphasizes that CD should be considered i...

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Autores principales: Stanton, Brielle, Caza, Tiffany, Huang, Dongmei, Beg, Mirza B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340656/
https://www.ncbi.nlm.nih.gov/pubmed/28286790
http://dx.doi.org/10.14309/crj.2017.24
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author Stanton, Brielle
Caza, Tiffany
Huang, Dongmei
Beg, Mirza B.
author_facet Stanton, Brielle
Caza, Tiffany
Huang, Dongmei
Beg, Mirza B.
author_sort Stanton, Brielle
collection PubMed
description Tubulointerstitial nephritis (TIN) is not commonly associated in aminosalicylate-naïve patients with Crohn’s disease (CD). Our case describes the initial presentation, diagnosis, and management of an adolescent presenting with TIN and underlying CD. Our case emphasizes that CD should be considered in the differential diagnosis of interstitial nephritis as not only a medication-related effect, but also as an extraintestinal manifestation of CD. We also describe successful management of undiagnosed recurring and symptomatic CD-related TIN with infliximab.
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spelling pubmed-53406562017-03-10 Tubulointerstitial Nephritis as the Initial Presentation of Crohn’s Disease and Successful Treatment with Infliximab Stanton, Brielle Caza, Tiffany Huang, Dongmei Beg, Mirza B. ACG Case Rep J Case Report Tubulointerstitial nephritis (TIN) is not commonly associated in aminosalicylate-naïve patients with Crohn’s disease (CD). Our case describes the initial presentation, diagnosis, and management of an adolescent presenting with TIN and underlying CD. Our case emphasizes that CD should be considered in the differential diagnosis of interstitial nephritis as not only a medication-related effect, but also as an extraintestinal manifestation of CD. We also describe successful management of undiagnosed recurring and symptomatic CD-related TIN with infliximab. American College of Gastroenterology 2017-02-15 /pmc/articles/PMC5340656/ /pubmed/28286790 http://dx.doi.org/10.14309/crj.2017.24 Text en Copyright © Stanton et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Stanton, Brielle
Caza, Tiffany
Huang, Dongmei
Beg, Mirza B.
Tubulointerstitial Nephritis as the Initial Presentation of Crohn’s Disease and Successful Treatment with Infliximab
title Tubulointerstitial Nephritis as the Initial Presentation of Crohn’s Disease and Successful Treatment with Infliximab
title_full Tubulointerstitial Nephritis as the Initial Presentation of Crohn’s Disease and Successful Treatment with Infliximab
title_fullStr Tubulointerstitial Nephritis as the Initial Presentation of Crohn’s Disease and Successful Treatment with Infliximab
title_full_unstemmed Tubulointerstitial Nephritis as the Initial Presentation of Crohn’s Disease and Successful Treatment with Infliximab
title_short Tubulointerstitial Nephritis as the Initial Presentation of Crohn’s Disease and Successful Treatment with Infliximab
title_sort tubulointerstitial nephritis as the initial presentation of crohn’s disease and successful treatment with infliximab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340656/
https://www.ncbi.nlm.nih.gov/pubmed/28286790
http://dx.doi.org/10.14309/crj.2017.24
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AT huangdongmei tubulointerstitialnephritisastheinitialpresentationofcrohnsdiseaseandsuccessfultreatmentwithinfliximab
AT begmirzab tubulointerstitialnephritisastheinitialpresentationofcrohnsdiseaseandsuccessfultreatmentwithinfliximab

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