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Analysis of the Serotonergic System in a Mouse Model of Rett Syndrome Reveals Unusual Upregulation of Serotonin Receptor 5b
Mutations in the transcription factor methyl-CpG-binding-protein 2 (MeCP2) cause a delayed-onset neurodevelopmental disorder known as Rett syndrome (RTT). Although alteration in serotonin levels have been reported in RTT patients, the molecular mechanisms underlying these defects are not well unders...
Autores principales: | Vogelgesang, Steffen, Niebert, Sabine, Renner, Ute, Möbius, Wiebke, Hülsmann, Swen, Manzke, Till, Niebert, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340760/ https://www.ncbi.nlm.nih.gov/pubmed/28337123 http://dx.doi.org/10.3389/fnmol.2017.00061 |
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