Cargando…

MAGE-A Antigens and Cancer Immunotherapy

MAGE-A antigens are expressed in a variety of cancers of diverse histological origin and germinal cells. Due to their relatively high tumor specificity, they represent attractive targets for active specific and adoptive cancer immunotherapies. Here, we (i) review past and ongoing clinical studies ta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zajac, Paul, Schultz-Thater, Elke, Tornillo, Luigi, Sadowski, Charlotte, Trella, Emanuele, Mengus, Chantal, Iezzi, Giandomenica, Spagnoli, Giulio C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340762/ https://www.ncbi.nlm.nih.gov/pubmed/28337438 http://dx.doi.org/10.3389/fmed.2017.00018

Ejemplares similares

Whole blood assessment of antigen specific cellular immune response by real time quantitative PCR: a versatile monitoring and discovery tool
por: Schultz-Thater, Elke, et al.
Publicado: (2008)

A replication-incompetent CD154/40L recombinant vaccinia virus induces direct and macrophage-mediated antitumor effects in vitro and in vivo
por: Governa, Valeria, et al.
Publicado: (2019)

Immunohistochemical analysis of the expression of MAGE-A and NY-ESO-1 cancer/testis antigens in diffuse large B-cell testicular lymphoma
por: Hudolin, Tvrtko, et al.
Publicado: (2013)

Colorectal carcinoma infiltration by myeloperoxidase-expressing neutrophil granulocytes is associated with favorable prognosis
por: Hirt, Christian, et al.
Publicado: (2013)

Elevated levels of circulating IL-7 and IL-15 in patients with early stage prostate cancer
por: Mengus, Chantal, et al.
Publicado: (2011)

NY-ESO-1 tumour associated antigen is a cytoplasmic protein detectable by specific monoclonal antibodies in cell lines and clinical specimens
por: Schultz-Thater, E, et al.
Publicado: (2000)

Migration and Function of Antigen-Primed Nonpolarized T Lymphocytes in Vivo
por: Iezzi, Giandomenica, et al.
Publicado: (2001)

Expression and Immune Responses to MAGE Antigens Predict Survival in Epithelial Ovarian Cancer
por: Daudi, Sayeema, et al.
Publicado: (2014)

Expression of MAGE-A and NY-ESO-1 cancer/testis antigens in medullary breast cancer: a retrospective immunohistochemical study
por: Matković, Božica, et al.
Publicado: (2011)

TIA-1 Cytotoxic Granule-Associated RNA Binding Protein Improves the Prognostic Performance of CD8 in Mismatch Repair-Proficient Colorectal Cancer
por: Zlobec, Inti, et al.
Publicado: (2010)

The Melanoma-Associated Antigen Family A (MAGE-A): A Promising Target for Cancer Immunotherapy?
por: Alsalloum, Alaa, et al.
Publicado: (2023)

Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment
por: Däster, Silvio, et al.
Publicado: (2016)

High Myeloperoxidase Positive Cell Infiltration in Colorectal Cancer Is an Independent Favorable Prognostic Factor
por: Droeser, Raoul A., et al.
Publicado: (2013)

Combinational expression of tumor testis antigens NY-ESO-1, MAGE-A3, and MAGE-A4 predicts response to immunotherapy in mucosal melanoma patients
por: Freiberger, Sandra N., et al.
Publicado: (2022)

Gastrointestinal Stromal Tumor – An Evolving Concept
por: Tornillo, Luigi
Publicado: (2014)

Melanoma Cells Present a MAGE-3 Epitope to CD4(+) Cytotoxic T Cells in Association with Histocompatibility Leukocyte Antigen DR11
por: Manici, Simona, et al.
Publicado: (1999)

High Frequency of CD8 Positive Lymphocyte Infiltration Correlates with Lack of Lymph Node Involvement in Early Rectal Cancer
por: Däster, Silvio, et al.
Publicado: (2014)

Evolutionary History of the Cancer Immunity Antigen MAGE Gene Family
por: Katsura, Yukako, et al.
Publicado: (2011)

MAGE-A3-specific anticancer immunotherapy in the clinical practice
por: Brichard, Vincent G, et al.
Publicado: (2013)

MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy
por: Laban, Simon, et al.
Publicado: (2017)

IL-22-mediates Cross-talk between Tumor Cells and Immune Cells Associated with Favorable Prognosis in Human Colorectal Cancer
por: Droeser, Raoul André, et al.
Publicado: (2021)

Low Expression of Programmed Death 1 (PD-1), PD-1 Ligand 1 (PD-L1), and Low CD8+ T Lymphocyte Infiltration Identify a Subgroup of Patients With Gastric and Esophageal Adenocarcinoma With Severe Prognosis
por: Däster, Silvio, et al.
Publicado: (2020)

Co-expression of cancer-testis antigens of MAGE-A6 and MAGE-A11 is associated with tumor aggressiveness in patients with bladder cancer
por: Mohsenzadegan, Monireh, et al.
Publicado: (2022)

Multiple mechanisms underlie defective recognition of melanoma cells cultured in three-dimensional architectures by antigen-specific cytotoxic T lymphocytes
por: Feder-Mengus, C, et al.
Publicado: (2007)

T‐cadherin in prostate cancer: relationship with cancer progression, differentiation and drug resistance
por: Dasen, Boris, et al.
Publicado: (2016)

Expression of cancer/testis antigens MAGE-A, MAGE-C1, GAGE and CTAG1B in benign and malignant thyroid diseases
por: Melo, Daniel Hardy, et al.
Publicado: (2017)

OX40 expression enhances the prognostic significance of CD8 positive lymphocyte infiltration in colorectal cancer
por: Weixler, Benjamin, et al.
Publicado: (2015)

MAGE-A10 Protein Expression in Advanced High Grade Serous Ovarian Cancer Is Associated with Resistance to First-Line Platinum-Based Chemotherapy
por: Lisica Šikić, Nataša, et al.
Publicado: (2023)

Publisher Correction: Co-expression of cancer-testis antigens of MAGE-A6 and MAGE-A11 is associated with tumor aggressiveness in patients with bladder cancer
por: Mohsenzadegan, Monireh, et al.
Publicado: (2022)

Expression of melanoma antigen-encoding genes (MAGE) by common primers for MAGE-A1 to -A6 in colorectal carcinomas among Koreans.
por: Park, Myeng-Sun, et al.
Publicado: (2002)

MAGE cancer-testis antigens protect the mammalian germline under environmental stress
por: Fon Tacer, Klementina, et al.
Publicado: (2019)

T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4
por: Coles, Charlotte H., et al.
Publicado: (2020)

Pathogenicity of the MAGE family
por: Li, Sanyan, et al.
Publicado: (2021)

In vivo enhancement of the MAGE-specific cellular immune response by a recombinant MAGE1-MAGE3-TBHSP70 tumor vaccine
por: Junwei, Wang, et al.
Publicado: (2016)

Expression of MAGE-1 and -3 genes and gene products in human hepatocellular carcinoma
por: Kariyama, K, et al.
Publicado: (1999)

Deep Learning-Based Pathology Image Analysis Enhances Magee Feature Correlation With Oncotype DX Breast Recurrence Score
por: Li, Hongxiao, et al.
Publicado: (2022)

MAGE, BAGE and GAGE: tumour antigen expression in benign and malignant ovarian tissue.
por: Gillespie, A. M., et al.
Publicado: (1998)

Erratum to: In vivo enhancement of the MAGE-specific cellular immune response by a recombinant MAGE1-MAGE3-TBHSP70 tumor vaccine
por: Junwei, Wang, et al.
Publicado: (2017)

Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-β
por: Mele, Valentina, et al.
Publicado: (2014)

Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer
por: Lugli, A, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_tv7b4ul43tma5eq7nofjiab4m5