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Bone Marrow-Derived Cell Accumulation in the Spinal Cord Is Independent of Peripheral Mobilization in a Mouse Model of Amyotrophic Lateral Sclerosis

Bone marrow-derived cells (BMDCs) are capable of migrating across the blood–brain barrier (BBB) and accumulating in the central nervous system (CNS) when transplanted into recipients conditioned with whole-body irradiation or chemotherapy. We used the chemotherapeutic agents busulfan and treosulfan...

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Detalles Bibliográficos
Autores principales: Peake, Kyle, Manning, John, Lewis, Coral-Ann, Tran, Kevin, Rossi, Fabio, Krieger, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340765/
https://www.ncbi.nlm.nih.gov/pubmed/28337172
http://dx.doi.org/10.3389/fneur.2017.00075

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