Cargando…
Hypofractionated Irradiation Has Immune Stimulatory Potential and Induces a Timely Restricted Infiltration of Immune Cells in Colon Cancer Tumors
In addition to locally controlling the tumor, hypofractionated radiotherapy (RT) particularly aims to activate immune cells in the RT-modified microenvironment. Therefore, we examined whether hypofractionated RT can activate dendritic cells (DCs), induce immune cell infiltration in tumors, and how t...
Autores principales: | Frey, Benjamin, Rückert, Michael, Weber, Julia, Mayr, Xaver, Derer, Anja, Lotter, Michael, Bert, Christoph, Rödel, Franz, Fietkau, Rainer, Gaipl, Udo S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340766/ https://www.ncbi.nlm.nih.gov/pubmed/28337197 http://dx.doi.org/10.3389/fimmu.2017.00231 |
Ejemplares similares
-
Clonogenicity-based radioresistance determines the expression of immune suppressive immune checkpoint molecules after hypofractionated irradiation of MDA-MB-231 triple-negative breast cancer cells
por: Gehre, Simon, et al.
Publicado: (2023) -
Head and neck tumor cells treated with hypofractionated irradiation die via apoptosis and are better taken up by M1-like macrophages
por: Wedekind, Hanna, et al.
Publicado: (2021) -
Modern Radiotherapy Concepts and the Impact of Radiation on Immune Activation
por: Deloch, Lisa, et al.
Publicado: (2016) -
Low-Dose Radiotherapy Has No Harmful Effects on Key Cells of Healthy Non-Inflamed Joints
por: Deloch, Lisa, et al.
Publicado: (2018) -
Hypofractionated Radiotherapy Upregulates Several Immune Checkpoint Molecules in Head and Neck Squamous Cell Carcinoma Cells Independently of the HPV Status While ICOS-L Is Upregulated Only on HPV-Positive Cells
por: Wimmer, Sebastian, et al.
Publicado: (2021)