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hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma

AIM: To screen clinically relevant microRNAs (miRNAs) silenced by DNA methylation in human hepatocellular carcinoma (HCC). METHODS: Knockdown of DNA methyltransferases (DNMTs) using siRNAs and miRNA profiling in HCC cell lines were performed to identify DNA hypermethylation-mediated miRNA downregula...

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Detalles Bibliográficos
Autores principales: Anwar, Sumadi Lukman, Krech, Till, Hasemeier, Britta, Schipper, Elisa, Schweitzer, Nora, Vogel, Arndt, Kreipe, Hans, Buurman, Reena, Skawran, Britta, Lehmann, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340808/
https://www.ncbi.nlm.nih.gov/pubmed/28321157
http://dx.doi.org/10.3748/wjg.v23.i9.1568

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