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Autophagy Is a Protective Response to the Oxidative Damage to Endplate Chondrocytes in Intervertebral Disc: Implications for the Treatment of Degenerative Lumbar Disc

Low back pain (LBP) is the leading cause of disability in the elderly. Intervertebral disc degeneration (IDD) was considered as the main cause for LBP. Degeneration of cartilaginous endplate was a crucial harmful factor during the initiation and development of IDD. Oxidative stress was implicated in...

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Detalles Bibliográficos
Autores principales: Chen, Ke, Lv, Xiaohua, Li, Wei, Yu, Fei, Lin, Jianjing, Ma, Junxuan, Xiao, Deming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340961/
https://www.ncbi.nlm.nih.gov/pubmed/28321270
http://dx.doi.org/10.1155/2017/4041768

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