Engineered LINE-1 retrotransposition in nondividing human neurons

Half the human genome is made of transposable elements (TEs), whose ongoing activity continues to impact our genome. LINE-1 (or L1) is an autonomous non-LTR retrotransposon in the human genome, comprising 17% of its genomic mass and containing an average of 80–100 active L1s per average genome that...

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Detalles Bibliográficos
Autores principales: Macia, Angela, Widmann, Thomas J., Heras, Sara R., Ayllon, Veronica, Sanchez, Laura, Benkaddour-Boumzaouad, Meriem, Muñoz-Lopez, Martin, Rubio, Alejandro, Amador-Cubero, Suyapa, Blanco-Jimenez, Eva, Garcia-Castro, Javier, Menendez, Pablo, Ng, Philip, Muotri, Alysson R., Goodier, John L., Garcia-Perez, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340962/
https://www.ncbi.nlm.nih.gov/pubmed/27965292
http://dx.doi.org/10.1101/gr.206805.116

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