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Identification of Topological Network Modules in Perturbed Protein Interaction Networks

Biological networks consist of functional modules, however detecting and characterizing such modules in networks remains challenging. Perturbing networks is one strategy for identifying modules. Here we used an advanced mathematical approach named topological data analysis (TDA) to interrogate two p...

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Detalles Bibliográficos
Autores principales: Sardiu, Mihaela E., Gilmore, Joshua M., Groppe, Brad, Florens, Laurence, Washburn, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341041/
https://www.ncbi.nlm.nih.gov/pubmed/28272416
http://dx.doi.org/10.1038/srep43845

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