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PD-1 inhibitors increase the incidence and risk of pneumonitis in cancer patients in a dose-independent manner: a meta-analysis

Therapies that targeted PD-1 have shown remarkable rates of durable clinical responses in patients with various tumor types. However, the extent and knowledge of pulmonary toxicities associated with PD-1 blockade, mainly manifested as pneumonitis, remains obscure. In this study, a total of 6360 subj...

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Detalles Bibliográficos
Autores principales: Wu, Jiaying, Hong, Dongsheng, Zhang, Xiangnan, Lu, Xiaoyang, Miao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341153/
https://www.ncbi.nlm.nih.gov/pubmed/28272463
http://dx.doi.org/10.1038/srep44173