Cargando…
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function
Tristetraprolin (TTP) is an RNA-binding protein that post-transcriptionally suppresses gene expression by delivering mRNA cargo to processing bodies (P-bodies) where the mRNA is degraded. TTP functions as a tumor suppressor in a mouse model of B cell lymphoma, and in some human malignancies low TTP...
Autores principales: | Berglund, Anders E., Scott, Kristen E.N., Li, Weimin, Yang, Chunying, Fernandez, Mario R., Schaub, Franz X., Cleveland, John L., Rounbehler, Robert J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341258/ https://www.ncbi.nlm.nih.gov/pubmed/27825143 http://dx.doi.org/10.18632/oncotarget.13128 |
Ejemplares similares
-
CREB Targets Define the Gene Expression Signature of Malignancies Having Reduced Levels of the Tumor Suppressor Tristetraprolin
por: Fallahi, Mohammad, et al.
Publicado: (2014) -
Disrupting the MYC-TFEB Circuit Impairs Amino Acid Homeostasis and Provokes Metabolic Anergy
por: Fernandez, Mario R., et al.
Publicado: (2022) -
Roles of Tristetraprolin in Tumorigenesis
por: Park, Jeong-Min, et al.
Publicado: (2018) -
Expression of the mRNA stability regulator Tristetraprolin is required for lactation maintenance in the mouse mammary gland
por: Goddio, María Victoria, et al.
Publicado: (2018) -
Role of Tristetraprolin in the Resolution of Inflammation
por: Rappl, Peter, et al.
Publicado: (2021)