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Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function

Tristetraprolin (TTP) is an RNA-binding protein that post-transcriptionally suppresses gene expression by delivering mRNA cargo to processing bodies (P-bodies) where the mRNA is degraded. TTP functions as a tumor suppressor in a mouse model of B cell lymphoma, and in some human malignancies low TTP...

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Detalles Bibliográficos
Autores principales: Berglund, Anders E., Scott, Kristen E.N., Li, Weimin, Yang, Chunying, Fernandez, Mario R., Schaub, Franz X., Cleveland, John L., Rounbehler, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341258/
https://www.ncbi.nlm.nih.gov/pubmed/27825143
http://dx.doi.org/10.18632/oncotarget.13128

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