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An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele

Natural killer (NK) cells are known to play a role in mediating innate immunity, in enhancing adaptive immune responses, and have been implicated in mediating anti-tumor responses via antibody-dependent cell-mediated cytotoxicity (ADCC) by reactivity of CD16 with the Fc region of human IgG1 antibodi...

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Detalles Bibliográficos
Autores principales:	Jochems, Caroline, Hodge, James W., Fantini, Massimo, Fujii, Rika, Maurice, Y. Morillon, Greiner, John W., Padget, Michelle R., Tritsch, Sarah R., Tsang, Kwong Yok, Campbell, Kerry S., Klingemann, Hans, Boissel, Laurent, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Schlom, Jeffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341330/ https://www.ncbi.nlm.nih.gov/pubmed/27861156 http://dx.doi.org/10.18632/oncotarget.13411

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