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Methods of defining the non-inferiority margin in randomized, double-blind controlled trials: a systematic review

BACKGROUND: There is no consensus on the preferred method for defining the non-inferiority margin in non-inferiority trials, and previous studies showed that the rationale for its choice is often not reported. This study investigated how the non-inferiority margin is defined in the published literat...

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Detalles Bibliográficos
Autores principales:	Althunian, Turki A., de Boer, Anthonius, Klungel, Olaf H., Insani, Widya N., Groenwold, Rolf H. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341347/ https://www.ncbi.nlm.nih.gov/pubmed/28270184 http://dx.doi.org/10.1186/s13063-017-1859-x

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