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Cyproterone acetate enhances TRAIL-induced androgen-independent prostate cancer cell apoptosis via up-regulation of death receptor 5

BACKGROUND: Virtually all prostate cancer deaths occur due to obtaining the castration-resistant phenotype after prostate cancer cells escaped from apoptosis and/or growth suppression initially induced by androgen receptor blockade. TNF-related apoptosis-inducing ligand (TRAIL) was an attractive can...

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Detalles Bibliográficos
Autores principales:	Chen, Linjie, Wolff, Dennis W., Xie, Yan, Lin, Ming-Fong, Tu, Yaping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341373/ https://www.ncbi.nlm.nih.gov/pubmed/28270124 http://dx.doi.org/10.1186/s12885-017-3153-4

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