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Oligonucleotides targeting coagulation factor mRNAs: use in thrombosis and hemophilia research and therapy
Small interfering (si) RNAs and antisense oligonucleotides (ASOs; here for simplicity reasons, both referred to as oligonucleotides) are small synthetic RNA or DNA molecules with a sequence complementary to a (pre)mRNA. Although the basic mechanisms of action between siRNAs and ASO are distinct, a s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341404/ https://www.ncbi.nlm.nih.gov/pubmed/28286423 http://dx.doi.org/10.1186/s12959-017-0130-8 |