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Multiplex serum protein analysis reveals potential mechanisms and markers of response to hyperimmune caprine serum in systemic sclerosis

BACKGROUND: Hyperimmune caprine serum (HICS) is a novel biological therapy with potential benefit for skin in established diffuse cutaneous systemic sclerosis. Here we report multiplex protein analysis of blood samples from a placebo-controlled phase II clinical trial and explore mechanisms of actio...

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Detalles Bibliográficos
Autores principales: Quillinan, Niamh, Clark, Kristina E. N., Youl, Bryan, Vernes, Jeffrey, McIntosh, Deirdre, Haq, Syed, Denton, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341430/
https://www.ncbi.nlm.nih.gov/pubmed/28270187
http://dx.doi.org/10.1186/s13075-017-1252-x