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Genetic variants in SERPINA4 and SERPINA5, but not BCL2 and SIK3 are associated with acute kidney injury in critically ill patients with septic shock

BACKGROUND: Acute kidney injury (AKI) is a multifactorial syndrome, but knowledge about its pathophysiology and possible genetic background is limited. Recently the first hypothesis-free genetic association studies have been published to explore individual susceptibility to AKI. We aimed to replicat...

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Detalles Bibliográficos
Autores principales: Vilander, Laura M., Kaunisto, Mari A., Vaara, Suvi T., Pettilä, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341446/
https://www.ncbi.nlm.nih.gov/pubmed/28270177
http://dx.doi.org/10.1186/s13054-017-1631-3