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Benchmarking and refining probability-based models for nucleosome-DNA interaction

BACKGROUND: In investigations of nucleosome positioning preferences, a model that assigns an affinity to a given sequence is necessary to make predictions. One important class of models, which treats a nucleosome sequence as a Markov chain, has been applied with success when informed with experiment...

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Detalles Bibliográficos
Autores principales: Tompitak, Marco, Barkema, Gerard T., Schiessel, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341481/
https://www.ncbi.nlm.nih.gov/pubmed/28270095
http://dx.doi.org/10.1186/s12859-017-1569-0