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Benchmarking and refining probability-based models for nucleosome-DNA interaction
BACKGROUND: In investigations of nucleosome positioning preferences, a model that assigns an affinity to a given sequence is necessary to make predictions. One important class of models, which treats a nucleosome sequence as a Markov chain, has been applied with success when informed with experiment...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341481/ https://www.ncbi.nlm.nih.gov/pubmed/28270095 http://dx.doi.org/10.1186/s12859-017-1569-0 |