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Many roads to symmetry breaking: molecular mechanisms and theoretical models of yeast cell polarity

Mathematical modeling has been instrumental in identifying common principles of cell polarity across diverse systems. These principles include positive feedback loops that are required to destabilize a spatially uniform state of the cell. The conserved small G-protein Cdc42 is a master regulator of...

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Detalles Bibliográficos
Autores principales: Goryachev, Andrew B., Leda, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341721/
https://www.ncbi.nlm.nih.gov/pubmed/28137950
http://dx.doi.org/10.1091/mbc.E16-10-0739

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