Sonic hedgehog pathway activation increases mitochondrial abundance and activity in hippocampal neurons

Mitochondria are essential organelles whose biogenesis, structure, and function are regulated by many signaling pathways. We present evidence that, in hippocampal neurons, activation of the Sonic hedgehog (Shh) signaling pathway affects multiple aspects of mitochondria. Mitochondrial mass was increa...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Pamela J., Manor, Uri, Petralia, Ronald S., Brose, Rebecca D., Wu, Ryan T. Y., Ott, Carolyn, Wang, Ya-Xian, Charnoff, Ari, Lippincott-Schwartz, Jennifer, Mattson, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341723/
https://www.ncbi.nlm.nih.gov/pubmed/27932496
http://dx.doi.org/10.1091/mbc.E16-07-0553

Ejemplares similares

Ejemplares similares