Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes

Prostate cancer (PCa) susceptibility is defined by a continuum from rare, high-penetrance to common, low-penetrance alleles. Research to date has concentrated on identification of variants at the ends of that continuum. Taking an alternate approach, we focused on the important but elusive class of l...

Descripción completa

Detalles Bibliográficos
Autores principales: Karyadi, Danielle M., Geybels, Milan S., Karlins, Eric, Decker, Brennan, McIntosh, Laura, Hutchinson, Amy, Kolb, Suzanne, McDonnell, Shannon K., Hicks, Belynda, Middha, Sumit, FitzGerald, Liesel M., DeRycke, Melissa S., Yeager, Meredith, Schaid, Daniel J., Chanock, Stephen J., Thibodeau, Stephen N., Berndt, Sonja I., Stanford, Janet L., Ostrander, Elaine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341753/
https://www.ncbi.nlm.nih.gov/pubmed/27902461
http://dx.doi.org/10.18632/oncotarget.13646

Ejemplares similares

Ejemplares similares