Cargando…

Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells

In prior work we reported that advanced stage, drug-resistant pancreatic cancer cells (the SW1990 line) can be sensitized to the EGFR-targeting tyrosine kinase inhibitors (TKIs) erlotinib and gefitinib by treatment with 1,3,4-O-Bu(3)ManNAc (Bioorg. Med. Chem. Lett. (2015) 25(6):1223-7). Here we prov...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mathew, Mohit P., Tan, Elaine, Saeui, Christopher T., Bovonratwet, Patawut, Sklar, Samuel, Bhattacharya, Rahul, Yarema, Kevin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341816/ https://www.ncbi.nlm.nih.gov/pubmed/27613843 http://dx.doi.org/10.18632/oncotarget.11582

Ejemplares similares

Metabolic Glycoengineering Sensitizes Drug-Resistant Pancreatic Cancer Cells to Tyrosine Kinase Inhibitors Erlotinib and Gefitinib
por: Mathew, Mohit P., et al.
Publicado: (2015)

Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells
por: Tian, Yuan, et al.
Publicado: (2015)

Development of a novel method to evaluate sialylation of glycoproteins and analysis of gp96 sialylation in Hela, SW1990 and A549 cell lines
por: Liang, Yangui, et al.
Publicado: (2015)

Cell Line-, Protein-, and Sialoglycosite-Specific Control of Flux-Based Sialylation in Human Breast Cells: Implications for Cancer Progression
por: Saeui, Christopher T., et al.
Publicado: (2020)

Cell Surface and Membrane Engineering: Emerging Technologies and Applications
por: Saeui, Christopher T., et al.
Publicado: (2015)

Glycoengineering Human Neural and Adipose Stem Cells with Novel Thiol-Modified N-Acetylmannosamine (ManNAc) Analogs
por: Du, Jian, et al.
Publicado: (2021)

Lectin staining and Western blot data showing differential sialylation of nutrient-deprived cancer cells to sialic acid supplementation
por: Badr, Haitham A., et al.
Publicado: (2015)

S.W. Radiologists Association: Meeting at Gloucester in October 1990
Publicado: (1991)

S.W. Vascular Surgeons: Meeting Aqt Swansea, February 1990
Publicado: (1991)

Spreadsheet Tools for Quantifying Seepage Flux Across the GW-SW Interface
por: Ford, R. G., et al.
Publicado: (2021)

The Effect of Travel Distance on Outcomes for Hip Resurfacing Arthroplasty at a High-Volume Center
por: Shen, Tony S., et al.
Publicado: (2020)

Surgical Club of S.W. England: Meeting at Weston-Super-Mare, October 1990
Publicado: (1991)

COVID-19–Related Internet Search Patterns Among People in the United States: Exploratory Analysis
por: Shen, Tony S, et al.
Publicado: (2020)

Hip Resurfacing vs Total Hip Arthroplasty in Patients Younger than 35 Years: A Comparison of Revision Rates and Patient-Reported Outcomes
por: LeBrun, Drake G., et al.
Publicado: (2021)

Comparison of Surgical Time, Short-term Adverse Events, and Implant Placement Accuracy Between Manual, Robotic-assisted, and Computer-navigated Total Hip Arthroplasty: A Network Meta-analysis of Randomized Controlled Trials
por: Kunze, Kyle N., et al.
Publicado: (2022)

Male sex is an independent risk factor for patellar osteochondral fractures following acute patellar dislocation in pediatric patients
por: Retzky, Julia S., et al.
Publicado: (2023)

IgG sialylation occurs via the FcRn-mediated recycling pathway in endothelial cells
por: Glendenning, Leandre M., et al.
Publicado: (2023)

Establishment and characterization of the gemcitabine-resistant human pancreatic cancer cell line SW1990/gemcitabine
por: Yu, Yue, et al.
Publicado: (2019)

Rotator cuff repair in HIV-infected patients: an analysis of postoperative complications
por: Gu, Alex, et al.
Publicado: (2020)

The Use of Older Versus Newer Data in the National Surgical Quality Improvement Program Database Influences the Results of Total Hip Arthroplasty Outcomes Studies
por: Shultz, Blake N., et al.
Publicado: (2019)

Postoperative outcomes of subaxial cervical spine metastasis: Comparison among the anterior, posterior, and combined approaches
por: Luksanapruksa, Panya, et al.
Publicado: (2022)

Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death
por: Britain, Colleen M., et al.
Publicado: (2018)

Improving Immunotherapy Through Glycodesign
por: Buettner, Matthew J., et al.
Publicado: (2018)

Modern Internet Search Analytics and Total Joint Arthroplasty: What Are Patients Asking and Reading Online?
por: Shen, Tony S., et al.
Publicado: (2020)

Critical roles for EGFR and EGFR–HER2 clusters in EGF binding of SW620 human carcinoma cells
por: Wollman, Adam J. M., et al.
Publicado: (2022)

Eckol inhibits Reg3A-induced proliferation of human SW1990 pancreatic cancer cells
por: Zhang, Mengya, et al.
Publicado: (2019)

Preoperative High, as well as Low, Platelet Counts Correlate With Adverse Outcomes After Elective Total Hip Arthroplasty
por: Malpani, Rohil, et al.
Publicado: (2020)

Total Joint Arthroplasty During the COVID-19 Pandemic: A Scoping Review with Implications for Future Practice
por: Chen, Aaron Z., et al.
Publicado: (2021)

Sialylation of EGFR by ST6GAL1 induces receptor activation and modulates trafficking dynamics
por: Ankenbauer, Katherine E., et al.
Publicado: (2023)

Sialylation of EGFR by ST6GAL1 induces receptor activation and modulates trafficking dynamics
por: Ankenbauer, Katherine E., et al.
Publicado: (2023)

Potential Anti-Tumor Activity of Nardoguaianone L Isolated from Nardostachys jatamansi DC. in SW1990 Cells
por: Sang, Chun-Yan, et al.
Publicado: (2022)

Selectin Ligands Sialyl-Lewis a and Sialyl-Lewis x in Gastrointestinal Cancers
por: Trinchera, Marco, et al.
Publicado: (2017)

Silibinin induces G1 arrest, apoptosis and JNK/SAPK upregulation in SW1990 human pancreatic cancer cells
por: Zhang, Xiaokai, et al.
Publicado: (2018)

Stiehopus japonieus acidic mucopolysaccharide inhibits the proliferation of pancreatic cancer SW1990 cells through Hippo-YAP pathway
por: Li, Xiaoyu, et al.
Publicado: (2017)

Thermodynamic Analysis for the Refining Ability of Salt Flux for Aluminum Recycling
por: Hiraki, Takehito, et al.
Publicado: (2014)

Contemporary Analysis of Inconsistencies Between Physician-reported Disclosures at the AAOS Annual Meeting and Industry-reported Financial Disclosures in the Open Payments Database
por: Bovonratwet, Patawut, et al.
Publicado: (2022)

ST6Gal-I–mediated sialylation of the epidermal growth factor receptor modulates cell mechanics and enhances invasion
por: Rao, Tejeshwar C., et al.
Publicado: (2022)

A Carabrane-Type Sesquiterpenolide Carabrone from Carpesium cernuum Inhibits SW1990 Pancreatic Cancer Cells by Inducing Ferroptosis
por: Zheng, Yi-Dan, et al.
Publicado: (2022)

Automated synthesis of sialylated oligosaccharides
por: Esposito, Davide, et al.
Publicado: (2012)

The Role of Sialyl-Tn in Cancer
por: Munkley, Jennifer
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_j84ui7cho0q7rc0uitd7j64h95