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Limits and potential of targeted sequencing analysis of liquid biopsy in patients with lung and colon carcinoma
The circulating free tumor DNA (ctDNA) represents an alternative, minimally invasive source of tumor DNA for molecular profiling. Targeted sequencing with next generation sequencing (NGS) can assess hundred mutations starting from a low DNA input. We performed NGS analysis of ctDNA from 44 patients...
Autores principales: | Rachiglio, Anna Maria, Abate, Riziero Esposito, Sacco, Alessandra, Pasquale, Raffaella, Fenizia, Francesca, Lambiase, Matilde, Morabito, Alessandro, Montanino, Agnese, Rocco, Gaetano, Romano, Carmen, Nappi, Anna, Iaffaioli, Rosario Vincenzo, Tatangelo, Fabiana, Botti, Gerardo, Ciardiello, Fortunato, Maiello, Monica R., De Luca, Antonella, Normanno, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341823/ https://www.ncbi.nlm.nih.gov/pubmed/27448974 http://dx.doi.org/10.18632/oncotarget.10704 |
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